When you go to open Microsoft Office 2013 it keeps saying that the program failed to open. When you try to open the next time it will only open in safe mode, this works without a problem.
1. Check that you have no com addons enabled (go to options > advanced)
2. If this doesn’t work try updating your graphics drivers.
In our case we had a Toshiba Dynadock that was replicating the screen, updating the drivers for this fixed the problem.